Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05VJH
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| Former ID |
DNC014653
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| Drug Name |
N-methyl ryanodine-succinamidate
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| Synonyms |
N-methyl ryanodine-succinamidate; CHEMBL432278
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H42N2O11
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| Canonical SMILES |
CC1CCC2(C3(CC4(C5(C(C(C3(C5(C2(C1OC(=O)CCC(=O)NC)O4)O)O)OC(=O)C6=CC=CN6)(C(C)C)O)C)O)C)O
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| InChI |
1S/C30H42N2O11/c1-15(2)27(38)22(42-21(35)17-8-7-13-32-17)28(39)23(4)14-26(37)24(27,5)30(28,40)29(43-26)20(16(3)11-12-25(23,29)36)41-19(34)10-9-18(33)31-6/h7-8,13,15-16,20,22,32,36-40H,9-12,14H2,1-6H3,(H,31,33)/t16?,20-,22-,23+,24?,25?,26?,27?,28?,29?,30?/m1/s1
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| InChIKey |
RWAKHARTDYCRMC-QYQZIFBLSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ryanodine receptor 1 (RYR1) | Target Info | Inhibitor | [1] |
| Panther Pathway | Beta1 adrenergic receptor signaling pathway | |||
| Beta2 adrenergic receptor signaling pathway | ||||
| CCKR signaling map ST | ||||
| Reactome | Stimuli-sensing channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Amino- and guanidinoacylryanodines: basic ryanodine esters with enhanced affinity for the sarcoplasmic reticulum Ca(2+)-release channel. J Med Chem. 1993 May 14;36(10):1319-23. | |||
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