Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05RDM
|
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| Former ID |
DNC002235
|
|||
| Drug Name |
ISIS 122976
|
|||
| Drug Type |
Antisense drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | MEKK3 messenger RNA (MAP3K3 mRNA) | Target Info | . | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Neurotrophin signaling pathway | ||||
| GnRH signaling pathway | ||||
| HTLV-I infection | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Panther Pathway | B cell activation | |||
| EGF receptor signaling pathway | ||||
| FGF signaling pathway | ||||
| Pathway Interaction Database | p38 MAPK signaling pathway | |||
| Regulation of p38-alpha and p38-beta | ||||
| IL1-mediated signaling events | ||||
| TNF receptor signaling pathway | ||||
| Reactome | Interleukin-1 signaling | |||
| WikiPathways | Insulin Signaling | |||
| EGF/EGFR Signaling Pathway | ||||
| MAPK Cascade | ||||
| Structural Pathway of Interleukin 1 (IL-1) | ||||
| EBV LMP1 signaling | ||||
| TNF alpha Signaling Pathway | ||||
| IL-1 signaling pathway | ||||
| Interleukin-1 signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 6,498,035, Antisense modulation of MEKK3 expression. | |||
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