Drug Information
Drug General Information | Top | |||
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Drug ID |
D03NZV
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Former ID |
DIB000727
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Drug Name |
SC-236
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Synonyms |
SC-791; SC-872; COX-2 inhibitors (anticancer), Pfizer; COX-2 inhibitors (anticancer), Pharmacia
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Drug Type |
Small molecular drug
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Terminated | [1] | |
Company |
GD Searle & Co
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Structure |
Download2D MOL |
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Formula |
C16H11ClF3N3O2S
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Canonical SMILES |
C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)Cl
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InChI |
1S/C16H11ClF3N3O2S/c17-11-3-1-10(2-4-11)14-9-15(16(18,19)20)22-23(14)12-5-7-13(8-6-12)26(21,24)25/h1-9H,(H2,21,24,25)
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InChIKey |
NSQNZEUFHPTJME-UHFFFAOYSA-N
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CAS Number |
CAS 170569-86-5
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PubChem Compound ID |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012807) | |||
REF 2 | Cyclooxygenase (COX)-2-dependent effects of the inhibitor SC236 when combined with ionizing radiation in mammary tumor cells derived from HER-2/neu mice. Mol Cancer Ther. 2004 Apr;3(4):417-24. |
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