Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03HUX
|
|||
| Drug Name |
PCM-075
|
|||
| Synonyms |
Onvansertib
Click to Show/Hide
|
|||
| Indication | Acute myeloid leukaemia [ICD-11: 2A60] | Phase 2 | [1] | |
| Prostate cancer [ICD-11: 2C82.0; ICD-9: 185] | Phase 2 | [2] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z] | Phase 1 | [1] | ||
| Company |
TrovaGene San Diego, CA
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C24H27F3N8O3
|
|||
| Canonical SMILES |
CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO
|
|||
| InChI |
1S/C24H27F3N8O3/c1-33-6-8-34(9-7-33)15-3-5-18(38-24(25,26)27)17(12-15)30-23-29-13-14-2-4-16-20(22(28)37)32-35(10-11-36)21(16)19(14)31-23/h3,5,12-13,36H,2,4,6-11H2,1H3,(H2,28,37)(H,29,30,31)
|
|||
| InChIKey |
QHLVBNKYJGBCQJ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 1034616-18-6
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | ClinicalTrials.gov (NCT03414034) Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer. U.S. National Institutes of Health. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.