| Target and Pathway |
Top |
| Target(s) |
Polo-like kinase 1 (PLK1) |
Target Info
|
Inhibitor |
[1] |
|
KEGG Pathway
|
FoxO signaling pathway
|
|
Cell cycle
|
|
Oocyte meiosis
|
|
Progesterone-mediated oocyte maturation
|
|
Pathway Interaction Database
|
p73 transcription factor network
|
|
ATR signaling pathway
|
|
PLK1 signaling events
|
|
FoxO family signaling
|
|
FOXM1 transcription factor network
|
|
Validated transcriptional targets of TAp63 isoforms
|
|
Polo-like kinase signaling events in the cell cycle
|
|
Reactome
|
Polo-like kinase mediated events
|
|
Golgi Cisternae Pericentriolar Stack Reorganization
|
|
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
|
|
Phosphorylation of the APC/C
|
|
Phosphorylation of Emi1
|
|
Condensation of Prophase Chromosomes
|
|
Separation of Sister Chromatids
|
|
Resolution of Sister Chromatid Cohesion
|
|
Regulation of PLK1 Activity at G2/M Transition
|
|
Activation of NIMA Kinases NEK9, NEK6, NEK7
|
|
Loss of Nlp from mitotic centrosomes
|
|
Recruitment of mitotic centrosome proteins and complexes
|
|
Loss of proteins required for interphase microtubule organization?from the centrosome
|
|
Anchoring of the basal body to the plasma membrane
|
|
RHO GTPases Activate Formins
|
|
Mitotic Prometaphase
|
|
Cyclin A/B1 associated events during G2/M transition
|
|
WikiPathways
|
Mitotic Telophase/Cytokinesis
|
|
Mitotic Metaphase and Anaphase
|
|
Mitotic Prophase
|
|
Mitotic Prometaphase
|
|
Integrated Pancreatic Cancer Pathway
|
|
TNF alpha Signaling Pathway
|
|
Prostate Cancer
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
Integrated Breast Cancer Pathway
|
|
Integrated Cancer pathway
|
|
Mitotic G2-G2/M phases
|
|
Cell Cycle
|
|
APC/C-mediated degradation of cell cycle proteins
|
|
Regulation of toll-like receptor signaling pathway
|
