Drug Information
Drug General Information | Top | |||
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Drug ID |
D02XLC
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Former ID |
DNC006231
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Drug Name |
5-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
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Synonyms |
CHEMBL201723; 5-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H10N2O2
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Canonical SMILES |
CC1=CC2=C(C3=C1NC4=CC=CC=C43)C(=O)NC2=O
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InChI |
1S/C15H10N2O2/c1-7-6-9-12(15(19)17-14(9)18)11-8-4-2-3-5-10(8)16-13(7)11/h2-6,16H,1H3,(H,17,18,19)
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InChIKey |
IMEDEXINTFAKNV-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Poly [ADP-ribose] polymerase 1 (PARP1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Base excision repair | |||
NF-kappa B signaling pathway | ||||
Panther Pathway | FAS signaling pathway | |||
Pathway Interaction Database | Integrin-linked kinase signaling | |||
Caspase Cascade in Apoptosis | ||||
Notch-mediated HES/HEY network | ||||
Reactome | Dual Incision in GG-NER | |||
WikiPathways | FAS pathway and Stress induction of HSP regulation | |||
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | ||||
Nanoparticle triggered regulated necrosis | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Synthesis and structure-activity relationships of novel poly(ADP-ribose) polymerase-1 inhibitors. Bioorg Med Chem Lett. 2006 Feb 15;16(4):938-42. |
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