Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02UHP
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| Former ID |
DNC009363
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| Drug Name |
6,7-dibromoquinoline-5,8-dione
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| Synonyms |
6,7-dibromoquinoline-5,8-dione; CHEMBL488961; 18633-05-1; 6,7-Dibrom-5,8-dihydrochinolin-5,8-dion; NSC82128; AC1L5TKN; SCHEMBL6866292; AC1Q6K93; 6,7-dibromo-5,8-quinolindion; CTK4D9216; DTXSID40292366; CPZKOUMVYNIHQE-UHFFFAOYSA-N; BDBM50264041; NSC-82128
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H3Br2NO2
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| Canonical SMILES |
C1=CC2=C(C(=O)C(=C(C2=O)Br)Br)N=C1
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| InChI |
1S/C9H3Br2NO2/c10-5-6(11)9(14)7-4(8(5)13)2-1-3-12-7/h1-3H
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| InChIKey |
CPZKOUMVYNIHQE-UHFFFAOYSA-N
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| CAS Number |
CAS 18633-05-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | M-phase inducer phosphatase 2 (MPIP2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cell cycle | ||||
| Progesterone-mediated oocyte maturation | ||||
| MicroRNAs in cancer | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Wnt Signaling Pathway | ||||
| Pathway Interaction Database | PLK1 signaling events | |||
| FOXM1 transcription factor network | ||||
| p38 signaling mediated by MAPKAP kinases | ||||
| Aurora A signaling | ||||
| Reactome | Cyclin B2 mediated events | |||
| Cyclin A/B1 associated events during G2/M transition | ||||
| Cyclin A:Cdk2-associated events at S phase entry | ||||
| WikiPathways | Senescence and Autophagy in Cancer | |||
| MAPK Signaling Pathway | ||||
| Retinoblastoma (RB) in Cancer | ||||
| Prostate Cancer | ||||
| Integrated Breast Cancer Pathway | ||||
| Integrated Cancer pathway | ||||
| Mitotic G2-G2/M phases | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties. Bioorg Med Chem. 2008 Oct 1;16(19):9040-9. | |||
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