Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01OYS
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| Former ID |
DIB002788
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| Drug Name |
Cyclolignan picropodophyllin
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| Synonyms |
PPP; IGF-1R inhibitor (cancer), Karolinska
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| Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 1 | [1] | |
| Company |
Karolinska Institute
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation. Am J Cancer Res. 2011; 1(3): 356-361. | |||
| REF 2 | The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling. J Vasc Surg. 2007 Jul;46(1):108-15. | |||
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