Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01GLG
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| Former ID |
DNC002931
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| Drug Name |
Deoxythymidine
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| Synonyms |
Thymidine; thymidine; 50-89-5; deoxythymidine; 2'-Deoxythymidine; Beta-Thymidine; 5-Methyldeoxyuridine; Thymidin; DThyd; 5-Methyl-2'-deoxyuridine; Thymine-2-deoxyriboside; Thyminedeoxyriboside; Thymine-2-desoxyriboside; 5-Methyldeoxyurindine; dThd; Uridine, 2'-deoxy-5-methyl-; Thymine deoxyriboside; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; dT; UNII-VC2W18DGKR; Deoxyribothymidine; AI3-52267; 2'-thymidine; beta-D-Ribofuranoside, thymine-1 2-deoxy-; CCRIS 1283; CHEBI:17748
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H14N2O5
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| Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
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| InChI |
1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
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| InChIKey |
IQFYYKKMVGJFEH-XLPZGREQSA-N
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| CAS Number |
CAS 146183-25-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3221, 3514, 584044, 585552, 610621, 829296, 841406, 866851, 3139601, 6436454, 7890767, 7980785, 8012955, 8027291, 8145493, 8153560, 11108071, 15196472, 22394774, 24899996, 24900588, 26704873, 26706463, 26718291, 26737504, 26737509, 26754268, 29196250, 29215196, 29224823, 46393445, 48416620, 49684293, 49833280, 50054703, 53789080, 56385553, 57322955, 58874714, 79679336, 85165052, 87576219, 91702399, 92297558, 92712972, 103240092, 103851056, 104310262, 117584596, 118260657
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| ChEBI ID |
CHEBI:17748
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mycobacterium Thymidine monophosphate kinase (MycB tmk) | Target Info | Inhibitor | [1] |
| Thymidine kinase 1 (TK1) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4718). | |||
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