Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DYSI03
|
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| Drug Name |
ASP1951
|
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| Synonyms |
PTZ-522
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|
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| Drug Type |
Antibody
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Phase 1 | [1] | |
| Company |
Astellas Pharma; Potenza Therapeutics
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Activation-inducible TNFR family receptor (TNFRSF18) | Target Info | Agonist | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | Downstream signaling in naï | |||
| Reactome | TNFs bind their physiological receptors | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03799003) A Study of ASP1951 in Subjects With Advanced Solid Tumors. U.S. National Institutes of Health. | |||
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