Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DY7IP9
|
|||
| Drug Name |
12B9m
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Anaemia [ICD-11: 3A90; ICD-10: D64.8] | Preclinical | [1] | |
| Company |
Amgen
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepcidin (HAMP) | Target Info | Inhibitor | [2] |
| WikiPathways | Iron metabolism in placenta | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Targeting iron metabolism in drug discovery and delivery. Nat Rev Drug Discov. 2017 Jun;16(6):400-423. | |||
| REF 2 | Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys. AAPS J. 2010 Dec;12(4):646-57. | |||
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