| Target and Pathway |
Top |
| Target(s) |
Ubiquitin-protein ligase E3 Mdm2 (MDM2) |
Target Info
|
Inhibitor |
[2] |
|
KEGG Pathway
|
FoxO signaling pathway
|
|
Cell cycle
|
|
p53 signaling pathway
|
|
Ubiquitin mediated proteolysis
|
|
Endocytosis
|
|
PI3K-Akt signaling pathway
|
|
Thyroid hormone signaling pathway
|
|
Epstein-Barr virus infection
|
|
Pathways in cancer
|
|
Transcriptional misregulation in cancer
|
|
Viral carcinogenesis
|
|
Proteoglycans in cancer
|
|
MicroRNAs in cancer
|
|
Glioma
|
|
Prostate cancer
|
|
Melanoma
|
|
Bladder cancer
|
|
Chronic myeloid leukemia
|
|
Panther Pathway
|
Insulin/IGF pathway-protein kinase B signaling cascade
|
|
p53 pathway
|
|
Ubiquitin proteasome pathway
|
|
P53 pathway feedback loops 1
|
|
p53 pathway feedback loops 2
|
|
Pathway Interaction Database
|
ErbB4 signaling events
|
|
p73 transcription factor network
|
|
ATR signaling pathway
|
|
ATM pathway
|
|
Glucocorticoid receptor regulatory network
|
|
Sumoylation by RanBP2 regulates transcriptional repression
|
|
Direct p53 effectors
|
|
Regulation of Androgen receptor activity
|
|
Validated transcriptional targets of deltaNp63 isoforms
|
|
Aurora A signaling
|
|
Validated transcriptional targets of TAp63 isoforms
|
|
p53 pathway
|
|
Regulation of retinoblastoma protein
|
|
Reactome
|
AKT phosphorylates targets in the cytosol
|
|
Oxidative Stress Induced Senescence
|
|
Oncogene Induced Senescence
|
|
Trafficking of AMPA receptors
|
|
Constitutive Signaling by AKT1 E17K in Cancer
|
|
Stabilization of p53
|
|
WikiPathways
|
DNA Damage Response (only ATM dependent)
|
|
DNA Damage Response
|
|
ErbB Signaling Pathway
|
|
Senescence and Autophagy in Cancer
|
|
Tryptophan metabolism
|
|
G1 to S cell cycle control
|
|
Copper homeostasis
|
|
Bladder Cancer
|
|
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
|
|
PIP3 activates AKT signaling
|
|
Apoptosis
|
|
ATM Signaling Pathway
|
|
Retinoblastoma (RB) in Cancer
|
|
Integrated Pancreatic Cancer Pathway
|
|
Prostate Cancer
|
|
Signaling Pathways in Glioblastoma
|
|
Integrated Breast Cancer Pathway
|
|
Integrated Cancer pathway
|
|
Cell Cycle
|
|
Cell Cycle Checkpoints
|
|
TP53 Network
|
|
miRNA Regulation of DNA Damage Response
|
|
Androgen receptor signaling pathway
|
