Drug Information
Drug General Information | Top | |||
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Drug ID |
DS41PJ
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Drug Name |
ARV-471
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Drug Type |
Small molecular drug
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Indication | Breast cancer [ICD-11: 2C60-2C65; ICD-10: C50, C79.51] | Phase 1/2 | [1] | |
Company |
Arvinas
|
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT04072952) A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (mBC). U.S. National Institutes of Health. | |||
REF 2 | Targeting estrogen receptor alpha for degradation with PROTACs: A promising approach to overcome endocrine resistance. Eur J Med Chem. 2020 Nov 15;206:112689. |
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