Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DR7EV6
|
|||
| Drug Name |
ARO-AAT
|
|||
| Drug Type |
Small interfering RNA
|
|||
| Indication | Alopecia [ICD-11: ED70; ICD-9: 704.09] | Phase 2 | [1] | |
| Alpha-1 antitrypsin deficiency [ICD-11: 5C5A; ICD-10: E88.0, M79.3; ICD-9: 273.4] | Phase 1 | [2] | ||
| Company |
Arrowhead Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | SERPINA1 messenger RNA (SERPINA1 mRNA) | Target Info | . | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03946449) Study of ARO-AAT in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD). U.S. National Institutes of Health. | |||
| REF 2 | ClinicalTrials.gov (NCT03362242) Study of ARO-AAT in Normal Adult Volunteers. U.S. National Institutes of Health. | |||
| REF 3 | Clinical pipeline report, company report or official report of Arrowhead Pharmaceuticals. | |||
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