Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DPQ4U3
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| Drug Name |
BFF-122
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| Drug Type |
Small molecular drug
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| Indication | Cognitive impairment [ICD-11: 6D71; ICD-10: F06.7; ICD-9: 331.83] | Preclinical | [1] | |
| Schizophrenia [ICD-11: 6A20] | Preclinical | [1] | ||
| Structure |
 |
Download2D MOL |
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| Formula |
C17H21FN4O4
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| Canonical SMILES |
CC1COC2=C3N1CC(C(=O)C3=CC(=C2N4CCN(CC4)N)F)C(=O)O
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| InChI |
1S/C17H21FN4O4/c1-9-8-26-16-13-10(15(23)11(17(24)25)7-22(9)13)6-12(18)14(16)20-2-4-21(19)5-3-20/h6,9,11H,2-5,7-8,19H2,1H3,(H,24,25)/t9-,11?/m0/s1
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| InChIKey |
SBYIJFJAUBGBOA-FTNKSUMCSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Kynurenine oxoglutarate transaminase II (AADAT) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nat Rev Drug Discov. 2019 May;18(5):379-401. | |||
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