Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DP4KH3
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| Drug Name |
PF-07265807
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| Synonyms |
PF-5807; ARRY-067
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|
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Phase 1 | [1] | |
| Company |
Pfizer
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine-protein kinase Mer (MERTK) | Target Info | Inhibitor | [2] |
| Tyrosine-protein kinase UFO (AXL) | Target Info | Inhibitor | [2] | |
| NetPath Pathway | TSH Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathway Interaction Database | Validated transcriptional targets of deltaNp63 isoforms | |||
| Reactome | Cell surface interactions at the vascular wall | |||
| VEGFA-VEGFR2 Pathway | ||||
| WikiPathways | Cell surface interactions at the vascular wall | |||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT04458259) A Study of PF-07265807 In Participants With Advanced or Metastatic Solid Tumors. U.S. National Institutes of Health. | |||
| REF 2 | National Cancer Institute Drug Dictionary (drug name PF-07265807). | |||
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