Drug Information
| Drug General Information | Top | |||
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| Drug ID |
DNL2F1
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| Drug Name |
MK6-83
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| Synonyms |
1062271-24-2; UNII-RE9JUR6NT4; RE9JUR6NT4; 5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide; C16H20N2O2S2; 5-methyl-N-(2-(piperidin-1-yl)phenyl)thiophene-2-sulfonamide; 5-methyl-N-(2-piperidin-1-ylphenyl)thiophene-2-sulfonamide; 5-Methyl-N-(2-(1-piperidinyl)phenyl)-2-thiophenesulfonamide; GTPL9783; AOB6422; SYN5108; ZINC69572886; AKOS025147398; NCGC00402264-02; NCGC00402264-04; AS-16472; CID 18191179; HY-110238; CS-0033102; 2-Thiophenesulfonamide, 5-methyl-N-(2-(1-piperidinyl)phenyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Preclinical | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H20N2O2S2
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| Canonical SMILES |
CC1=CC=C(S1)S(=O)(=O)NC2=CC=CC=C2N3CCCCC3
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| InChI |
1S/C16H20N2O2S2/c1-13-9-10-16(21-13)22(19,20)17-14-7-3-4-8-15(14)18-11-5-2-6-12-18/h3-4,7-10,17H,2,5-6,11-12H2,1H3
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| InChIKey |
IRGYSXZCDAWOOC-UHFFFAOYSA-N
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| CAS Number |
CAS 1062271-24-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mucolipin-1 (TRPML1) | Target Info | Agonist | [2] |
| References | Top | |||
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| REF 1 | Lysosomes as a therapeutic target. Nat Rev Drug Discov. 2019 Dec;18(12):923-948. | |||
| REF 2 | ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020 Oct;182:104922. | |||
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