Drug Information
Drug General Information | Top | |||
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Drug ID |
DLKQ59
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Drug Name |
LH846
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Synonyms |
639052-78-1; LH-846; LH 846; N-(5-chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide; N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneacetamide; Benzeneacetamide, N-(5-chloro-6-methyl-2-benzothiazolyl)-; N-(5-chloro-6-methylbenzo[d]thiazol-2-yl)-2-phenylacetamide; N-(5-Chloro-6-methyl-benzothiazol-2-yl)-2-phenyl-acetamide; Oprea1_693221; CHEMBL4303305; SCHEMBL18921565; AOB3510; ZINC386312; BCP09669; EX-A2092; 3782AH; MFCD03786038; STK241276; AKOS000461714; CCG-357108; CS-1810; MCULE-4592612500; NCGC00371143-05; AK205552; AS-55880; DA-33437; HY-15704; FT-0768032; ST51028673; AP-970/41681903; N-(5-chloro-6-methylbenzothiazol-2-yl)-2-phenylacetamide
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Drug Type |
Small molecular drug
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Indication | Mood disorder [ICD-11: 6A60-6E23] | Preclinical | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H13ClN2OS
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Canonical SMILES |
CC1=CC2=C(C=C1Cl)N=C(S2)NC(=O)CC3=CC=CC=C3
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InChI |
1S/C16H13ClN2OS/c1-10-7-14-13(9-12(10)17)18-16(21-14)19-15(20)8-11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H,18,19,20)
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InChIKey |
DYHAMRNAHTWYKY-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Casein kinase 1 (CK1) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Circadian rhythm as a therapeutic target. Nat Rev Drug Discov. 2021 Apr;20(4):287-307. | |||
REF 2 | A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. |
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