Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DEV97R
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| Drug Name |
PK68
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| Synonyms |
2173556-69-7; SCHEMBL19807982; BCP32187; EX-A4768; PK-68;PK 68; HY-128348; CS-0099048
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Investigative | [1] | |
| Company |
Soochow University
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| Structure |
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Download2D MOL |
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| Formula |
C22H24N4O3S
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| Canonical SMILES |
CC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(S3)NC(=O)C)NC(=O)OC4CCCCC4
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| InChI |
1S/C22H24N4O3S/c1-13-19(26-22(28)29-17-6-4-3-5-7-17)10-16(12-23-13)15-8-9-18-20(11-15)30-21(25-18)24-14(2)27/h8-12,17H,3-7H2,1-2H3,(H,26,28)(H,24,25,27)
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| InChIKey |
DRCNWQYEKZTTEW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Receptor-interacting protein 1 (RIPK1) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis. Cell Death Dis. 2019 Jun 24;10(7):493. | |||
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