Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DE2CW9
|
|||
| Drug Name |
Eplontersen
|
|||
| Drug Type |
Antisense oligonucleotide
|
|||
| Indication | Amyloid polyneuropathy [ICD-11: 5D00.20] | Approved | [1] | |
| Company |
AstraZeneca
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transthyretin messenger RNA (TTR mRNA) | Target Info | . | [1] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Retinoid cycle disease events | |||
| The canonical retinoid cycle in rods (twilight vision) | ||||
| Non-integrin membrane-ECM interactions | ||||
| Retinoid metabolism and transport | ||||
| Amyloid formation | ||||
| WikiPathways | Visual phototransduction | |||
| Extracellular matrix organization | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 217388 | |||
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