Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DDC63W
|
|||
| Drug Name |
EPZ033294
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Preclinical | [1] | |
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | SET and MYND domain-containing protein 2 (SMYD2) | Target Info | Inhibitor | [1] |
| Pathway Interaction Database | p53 pathway | |||
| Reactome | PKMTs methylate histone lysines | |||
| WikiPathways | Histone Modifications | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease. Nat Rev Drug Discov. 2021 Apr;20(4):265-286. | |||
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