Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DD1ZV6
|
|||
| Drug Name |
BI 1358894
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Depression [ICD-11: 6A70-6A7Z] | Phase 2 | [1] | |
| Company |
Boehringer Ingelheim
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Short transient receptor potential channel 4 (TRPC4) | Target Info | Inhibitor | [2] |
| Short transient receptor potential channel 5 (TRPC5) | Target Info | Inhibitor | [2] | |
| Panther Pathway | Alzheimer disease-presenilin pathway | |||
| Reactome | TRP channels | |||
| Role of second messengers in netrin-1 signaling | ||||
| WikiPathways | Netrin-1 signaling | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT04423757) A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of Boehringer Ingelheim. | |||
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