Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DAQ4G0
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| Drug Name |
NC043
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| Synonyms |
15-oxospiramilactone; 1053172-87-4; Q35479640
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| Drug Type |
Small molecular drug
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| Indication | Neurodegenerative disorder [ICD-11: 8A20-8A23] | Preclinical | [1] | |
| Company |
Chinese Academy of Sciences
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| Structure |
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Download2D MOL |
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| Formula |
C22H30O4
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| Canonical SMILES |
CC12CCCC3(C1CC(C45C3CC(CC4)C(=C)C5=O)O)C(=O)COCC2
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| InChI |
1S/C22H30O4/c1-13-14-4-7-22(19(13)25)16(10-14)21-6-3-5-20(2,15(21)11-17(22)23)8-9-26-12-18(21)24/h14-17,23H,1,3-12H2,2H3/t14-,15+,16-,17+,20-,21-,22+/m0/s1
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| InChIKey |
RCPPZYXWUAJXMA-KGYWYPJXSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ubiquitin carboxyl-terminal hydrolase 30 (USP30) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30. Cell Res. 2014 Apr;24(4):482-96. | |||
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