Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DAD9V4
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| Drug Name |
GSK2643943A
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| Synonyms |
2449301-27-1; EX-A4538; s6878; HY-111458; CS-0041056
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Preclinical | [1] | |
| Company |
GlaxoSmithKline
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| Structure |
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Download2D MOL |
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| Formula |
C17H12FN3
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| Canonical SMILES |
C1=CC(=CC(=C1)F)C=CC2=CC3=C(C=C2)C(=C(N3)N)C#N
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| InChI |
1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+
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| InChIKey |
CGXBPMZRTMXEIA-SNAWJCMRSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ubiquitin carboxyl-terminal hydrolase 20 (USP20) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Deubiquitylating enzymes and drug discovery: emerging opportunities. Nat Rev Drug Discov. 2018 Jan;17(1):57-78. | |||
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