Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D8MNH5
|
|||
| Drug Name |
Evolocumab
|
|||
| Synonyms |
Repatha
Click to Show/Hide
|
|||
| Drug Type |
Monoclonal antibody
|
|||
| Indication | Heterozygous familial hypercholesterolemia [ICD-11: 5C80.00] | Approved | [1] | |
| Homozygous familial hypercholesterolemia [ICD-11: 5C80.00] | Approved | [1] | ||
| Company |
Amgen
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Proprotein convertase subtilisin/kexin type 9 (PCSK9) | Target Info | . | [2] |
| WikiPathways | PCSK9-mediated LDLR degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. | |||
| REF 2 | Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med. 2017 May 4;376(18):1713-1722. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.