Drug Information
Drug General Information | Top | |||
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Drug ID |
D6QA4N
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Drug Name |
S-(2-Aminophenyl)-L-cysteine S,S-dioxide
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Synonyms |
SCHEMBL9065263
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Drug Type |
Small molecular drug
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Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Preclinical | [1] | |
Structure |
Download2D MOL |
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Formula |
C9H12N2O4S
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Canonical SMILES |
C1=CC=C(C(=C1)N)S(=O)(=O)CC(C(=O)O)N
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InChI |
1S/C9H12N2O4S/c10-6-3-1-2-4-8(6)16(14,15)5-7(11)9(12)13/h1-4,7H,5,10-11H2,(H,12,13)/t7-/m0/s1
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InChIKey |
JJUXYMMPJKOKBD-ZETCQYMHSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Kynureninase (KYNU) | Target Info | Inhibitor | [2] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation | ||||
L-kynurenine degradation | ||||
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
NAD de novo biosynthesis | ||||
KEGG Pathway | Tryptophan metabolism | |||
Metabolic pathways | ||||
NetPath Pathway | TSLP Signaling Pathway | |||
Pathwhiz Pathway | Tryptophan Metabolism | |||
Reactome | Tryptophan catabolism | |||
WikiPathways | Tryptophan metabolism | |||
Metabolism of amino acids and derivatives | ||||
NAD Biosynthesis II (from tryptophan) | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nat Rev Drug Discov. 2019 May;18(5):379-401. | |||
REF 2 | Structure, mechanism, and substrate specificity of kynureninase. Biochim Biophys Acta. 2011 Nov;1814(11):1481-8. |
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