Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D58BFC
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| Drug Name |
Atuzaginstat
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| Synonyms |
Atuzaginstat; DGN7ROZ8EN; Atuzaginstat [INN]; UNII-DGN7ROZ8EN; 2211981-76-7; COR388; COR-388; Cyclopentanecarboxamide, N-((1S)-5-amino-1-(2-(2,3,6-trifluorophenoxy)acetyl)pentyl)-; N-((3S)-7-Amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamide; AtuzaginstatCOR388; CHEMBL5095230; SCHEMBL19972758; BDBM453275; EX-A6081; US10730826, Compound 1a-racemic; US10730826, Compound 1a-non-racemic; N-[(3S)-7-amino-2-oxo-1-(2,3,6-trifluorophenoxy)heptan-3-yl]cyclopentanecarboxamide
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| Drug Type |
Small molecule
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| Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Phase 2/3 | [1] | |
| Company |
Cortexyme
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H25F3N2O3
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| Canonical SMILES |
C1CCC(C1)C(=O)NC(CCCCN)C(=O)COC2=C(C=CC(=C2F)F)F
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| InChI |
InChI=1S/C19H25F3N2O3/c20-13-8-9-14(21)18(17(13)22)27-11-16(25)15(7-3-4-10-23)24-19(26)12-5-1-2-6-12/h8-9,12,15H,1-7,10-11,23H2,(H,24,26)/t15-/m0/s1
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| InChIKey |
OLIMBXKACVCIMM-HNNXBMFYSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03823404) GAIN Trial: A Randomized, Double-Blind, Placebo-Controlled Study of COR388 in Subjects With Alzheimer's Disease. U.S.National Institutes of Health. | |||
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