Drug Information
Drug General Information | Top | |||
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Drug ID |
D3NLJ9
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Drug Name |
Dusquetide
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Synonyms |
931395-42-5; UNII-IKX7W49NLN; RIVPA; (S)-1-(L-arginyl-L-isoleucyl-L-valyl)-N-((S)-1-amino-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; IKX7W49NLN; SGX94; SGX942; Dusquetide (USAN/INN); L-arginyl-L-isoleucyl-L-valyl-L-prolyl-L-alaninamide; SGX-94; CHEMBL3545314; SCHEMBL16671001; IMX-942; SGX-942; HY-P2076; CS-0107857; J3.575.671J; D11751; Q27280772; (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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Drug Type |
Peptide
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Indication | Oral cavity squamous cell carcinoma [ICD-11: 2B6E.0; ICD-9: 199] | Phase 3 | [1] | |
Oral mucositis [ICD-11: DA01.11; ICD-10: K12.3; ICD-9: 528] | Phase 3 | [1] | ||
Company |
Soligenix
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Structure |
Download2D MOL
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Formula |
C25H47N9O5
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Canonical SMILES |
CCC(C)C(C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)N)NC(=O)C(CCCN=C(N)N)N
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InChI |
1S/C25H47N9O5/c1-6-14(4)19(33-21(36)16(26)9-7-11-30-25(28)29)23(38)32-18(13(2)3)24(39)34-12-8-10-17(34)22(37)31-15(5)20(27)35/h13-19H,6-12,26H2,1-5H3,(H2,27,35)(H,31,37)(H,32,38)(H,33,36)(H4,28,29,30)/t14-,15-,16-,17-,18-,19-/m0/s1
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InChIKey |
ZUJBBVJXXYRPFS-DYKIIFRCSA-N
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PubChem Compound ID |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT03237325) DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer. U.S. National Institutes of Health. |
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