Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D3C9RJ
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| Drug Name |
LTI-03
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| Synonyms |
CSP7; UNII-JE7G34JYW4; CSP-7; JE7G34JYW4; LTI-03; Phe-Thr-Thr-Phe-Thr-Val-Thr; L-Threonine, L-phenylalanyl-L-threonyl-L-threonyl-L-phenylalanyl-L-threonyl-L-valyl-; 1504575-10-3
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| Drug Type |
Peptide
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| Indication | Idiopathic pulmonary fibrosis [ICD-11: CB03.4; ICD-10: J84.1; ICD-9: 516.3] | Phase 1 | [1] | |
| Company |
Lung Therapeutics
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| Structure |
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Download2D MOL
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| Formula |
C39H57N7O12
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| Canonical SMILES |
CC(C)C(C(=O)NC(C(C)O)C(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C(CC2=CC=CC=C2)N
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| InChI |
InChI=1S/C39H57N7O12/c1-19(2)28(35(53)46-32(23(6)50)39(57)58)42-37(55)31(22(5)49)44-34(52)27(18-25-15-11-8-12-16-25)41-36(54)29(20(3)47)45-38(56)30(21(4)48)43-33(51)26(40)17-24-13-9-7-10-14-24/h7-16,19-23,26-32,47-50H,17-18,40H2,1-6H3,(H,41,54)(H,42,55)(H,43,51)(H,44,52)(H,45,56)(H,46,53)(H,57,58)/t20-,21-,22-,23-,26+,27+,28+,29+,30+,31+,32+/m1/s1
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| InChIKey |
MPQBITKUSWZKQD-DVPOGPKQSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT04233814) A Randomized, Double-Blind, Placebo-Controlled, Ph 1a, First-in-Man, Single Ascending Dose & Multiple Ascending Dose Safety, Tolerability and PK Study of a Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03) in Healthy Adult Subjects. U.S.National Institutes of Health. | |||
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