Drug Information
Drug General Information | Top | |||
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Drug ID |
D18SHN
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Drug Name |
Tecartus
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Synonyms |
Brexucabtagene autoleucel; KTE-X19
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Drug Type |
CAR T Cell Therapy
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Indication | Mantle cell lymphoma [ICD-11: 2A85.5; ICD-10: C83.1] | Approved | [1] | |
Company |
Gilead Sciences; Kite Pharma
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Target and Pathway | Top | |||
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Target(s) | B-lymphocyte surface antigen B4 (CD19) | Target Info | . | [1] |
KEGG Pathway | PI3K-Akt signaling pathway | |||
Hematopoietic cell lineage | ||||
B cell receptor signaling pathway | ||||
Epstein-Barr virus infection | ||||
Primary immunodeficiency | ||||
NetPath Pathway | IL-7 Signaling Pathway | |||
Panther Pathway | B cell activation | |||
Pathway Interaction Database | BCR signaling pathway | |||
Reactome | PIP3 activates AKT signaling | |||
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | ||||
Constitutive Signaling by Aberrant PI3K in Cancer | ||||
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | ||||
WikiPathways | Human Complement System | |||
Signaling by the B Cell Receptor (BCR) | ||||
PIP3 activates AKT signaling | ||||
B Cell Receptor Signaling Pathway | ||||
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
References | Top | |||
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REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. |
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