Drug Information
Drug General Information | Top | |||
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Drug ID |
D12EFM
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Drug Name |
RG7854
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Drug Type |
Small molecular drug
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Indication | Hepatitis B virus infection [ICD-11: 1E51.0; ICD-10: B18.1] | Phase 1 | [1] | |
Company |
Roche
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Target and Pathway | Top | |||
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Target(s) | Toll-like receptor 7 (TLR7) | Target Info | Agonist | [1] |
KEGG Pathway | Toll-like receptor signaling pathway | |||
Measles | ||||
Influenza A | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Toll receptor signaling pathway | |||
Reactome | Trafficking and processing of endosomal TLR | |||
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | ||||
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | ||||
MyD88 dependent cascade initiated on endosome | ||||
WikiPathways | Toll-like receptor signaling pathway | |||
Toll-Like Receptors Cascades | ||||
MyD88 dependent cascade initiated on endosome | ||||
Trafficking and processing of endosomal TLR | ||||
Regulation of toll-like receptor signaling pathway |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of Roche. |
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