Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0ZW2F
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| Former ID |
DNC014892
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| Drug Name |
NSC-119910
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| Synonyms |
NSC119910; NSC-119910; CHEMBL487046; Gbetagamma Modulator I, M119; 2-(4,5,6-Trihydroxy-3-oxo-3H-xanthen-9-yl)-cyclohexane-1-carboxylic acid; AC1L6U1C; SCHEMBL2778459; cid_274122; SCHEMBL16556406; BDBM50246208; NCI60_000471; MLS-0111618.0001; 2-(4,6-trihydroxy-3-oxo-3H-xanthen-9-yl)cyclohexanecarboxylic acid; 2-(3,4,5-trihydroxy-6-oxo-xanthen-9-yl)cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 2-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)-; 2-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)cyclohexanecarboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Cardiac failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H18O7
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| Canonical SMILES |
C1CCC(C(C1)C2=C3C=CC(=O)C(=C3OC4=C2C=CC(=C4O)O)O)C(=O)O
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| InChI |
1S/C20H18O7/c21-13-7-5-11-15(9-3-1-2-4-10(9)20(25)26)12-6-8-14(22)17(24)19(12)27-18(11)16(13)23/h5-10,21,23-24H,1-4H2,(H,25,26)
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| InChIKey |
CAVIJGGXNIURPI-UHFFFAOYSA-N
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| CAS Number |
CAS 500533-94-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Heat shock protein 70 (HSP70) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
| REF 2 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | |||
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