Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0ZL6B
|
|||
Former ID |
DNC007187
|
|||
Drug Name |
1-hexadecyl-1H-indole-2,3-dione
|
|||
Synonyms |
1-hexadecyl-1H-indole-2,3-dione; C24H37NO2; 1-hexadecylindole-2,3-dione; AC1MXWVN; Isatin-based compound, 63; CHEMBL221512; BDBM22843; MolPort-000-704-286; STK527744; ZINC14979621; AKOS005460820; MCULE-4252873887; 28035-35-0
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C24H37NO2
|
|||
Canonical SMILES |
CCCCCCCCCCCCCCCCN1C2=CC=CC=C2C(=O)C1=O
|
|||
InChI |
1S/C24H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-20-25-22-19-16-15-18-21(22)23(26)24(25)27/h15-16,18-19H,2-14,17,20H2,1H3
|
|||
InChIKey |
JLUGWHXZCKLPBY-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
---|---|---|---|---|
REF 1 | Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. J Med Chem. 2007 Apr 19;50(8):1876-85. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.