Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ZK2G
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| Former ID |
DNC003165
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| Drug Name |
Monastrol
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| Synonyms |
monastrol; 329689-23-8; 254753-54-3; ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE; 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester; CHEBI:75382; ( inverted exclamation markA)-Monastrol; SR-01000357662; AC1MGLGQ; Probes2_000257; Probes2_000376; Probes1_000312; Probes1_000042; Probes1_000001; Oprea1_487786; Lopac0_000821; KBioSS_000613; CBDivE_015834; KBioGR_000613; BSPBio_001273; MLS006011746; SCHEMBL3168349; KBio3_001085; KBio2_000613
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H16N2O3S
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| Canonical SMILES |
CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
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| InChI |
1S/C14H16N2O3S/c1-3-19-13(18)11-8(2)15-14(20)16-12(11)9-5-4-6-10(17)7-9/h4-7,12,17H,3H2,1-2H3,(H2,15,16,20)
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| InChIKey |
LOBCDGHHHHGHFA-UHFFFAOYSA-N
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| CAS Number |
CAS 329689-23-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
533788, 3701249, 5195181, 7216298, 10025331, 10589536, 11114022, 11120339, 11120827, 11121315, 11121812, 11122292, 11144768, 11363027, 11365589, 11368151, 11371185, 11371186, 11373752, 11376313, 11444705, 12011217, 15345256, 24897267, 26752158, 26752159, 26759186, 34654246, 47290932, 47364980, 47364981, 47588794, 47736250, 47959526, 48034880, 48034881, 48259017, 48334256, 48334257, 50104807, 53800663, 57410084, 58023578, 79975183, 81093362, 84918195, 85774655, 85787266, 87700689, 88171891
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| ChEBI ID |
CHEBI:75382
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Kinesin-like protein KIF11 (KIF11) | Target Info | Inhibitor | [1] |
| Reactome | MHC class II antigen presentation | |||
| Kinesins | ||||
| WikiPathways | MHC class II antigen presentation | |||
| Kinesins | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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