Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0ZI0S
|
|||
Former ID |
DNC010303
|
|||
Drug Name |
7-methoxy-2-p-tolyl-4H-chromen-4-one
|
|||
Synonyms |
CHEMBL17052; 7-methoxy-2-(4-methylphenyl)chromen-4-one; 7-methoxy-2-(4-methylphenyl)-4H-chromen-4-one; 108980-49-0; 7-methoxy-2-p-tolyl-4H-chromen-4-one; AC1LIGD7; MolPort-000-450-862; ZINC522064; STK893155; BDBM50310185; 7-Methoxy-2-p-tolyl-chromen-4-one; AKOS002182021; MCULE-3043616847; NCGC00318207-01; 7-methoxy-2-(p-tolyl)-4H-chromen-4-one; ST50070846; VU0510077-1; AB01311569-01; 2-(4-Methylphenyl)-7-methoxy-4H-1-benzopyran-4-one
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C17H14O3
|
|||
Canonical SMILES |
CC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)OC
|
|||
InChI |
1S/C17H14O3/c1-11-3-5-12(6-4-11)16-10-15(18)14-8-7-13(19-2)9-17(14)20-16/h3-10H,1-2H3
|
|||
InChIKey |
OBNQAKAHHNLJHT-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation via tryptamine | ||||
Dopamine degradation | ||||
Putrescine degradation III | ||||
Noradrenaline and adrenaline degradation | ||||
KEGG Pathway | Glycine, serine and threonine metabolism | |||
Arginine and proline metabolism | ||||
Histidine metabolism | ||||
Tyrosine metabolism | ||||
Phenylalanine metabolism | ||||
Tryptophan metabolism | ||||
Drug metabolism - cytochrome P450 | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Dopaminergic synapse | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Alcoholism | ||||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5-Hydroxytryptamine degredation | ||||
Dopamine receptor mediated signaling pathway | ||||
Pathway Interaction Database | Alpha-synuclein signaling | |||
WikiPathways | Tryptophan metabolism | |||
Dopamine metabolism | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
---|---|---|---|---|
REF 1 | A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1273-9. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.