Drug Information
Drug General Information | Top | |||
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Drug ID |
D0ZH0T
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Former ID |
DNC010320
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Drug Name |
(+/-)-2-(4-fluorophenyl)chroman-4-one
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Synonyms |
4'-(Fluoro)flavanone; CHEMBL60720; 1840-02-4; 4h-1-benzopyran-4-one,2-(4-fluorophenyl)-2,3-dihydro-; 4'-Fluoroflavanone; (+/-)-2-(4-fluorophenyl)chroman-4-one; SCHEMBL2474548; CTK0E2543; DTXSID90452670; RFDPVHCUOLBALB-UHFFFAOYSA-N; BDBM50310197; AKOS030552931; KB-290728; 4H-1-Benzopyran-4-one, 2-(4-fluorophenyl)-2,3-dihydro-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H11FO2
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Canonical SMILES |
C1C(OC2=CC=CC=C2C1=O)C3=CC=C(C=C3)F
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InChI |
1S/C15H11FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-8,15H,9H2
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InChIKey |
RFDPVHCUOLBALB-UHFFFAOYSA-N
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CAS Number |
CAS 1840-02-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation via tryptamine | ||||
Dopamine degradation | ||||
Putrescine degradation III | ||||
Noradrenaline and adrenaline degradation | ||||
KEGG Pathway | Glycine, serine and threonine metabolism | |||
Arginine and proline metabolism | ||||
Histidine metabolism | ||||
Tyrosine metabolism | ||||
Phenylalanine metabolism | ||||
Tryptophan metabolism | ||||
Drug metabolism - cytochrome P450 | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Dopaminergic synapse | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Alcoholism | ||||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5-Hydroxytryptamine degredation | ||||
Dopamine receptor mediated signaling pathway | ||||
Pathway Interaction Database | Alpha-synuclein signaling | |||
WikiPathways | Tryptophan metabolism | |||
Dopamine metabolism | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1273-9. |
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