Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z8GS
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| Former ID |
DNC000666
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| Drug Name |
G-25
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| Synonyms |
SCHEMBL16529235; BDBM286896; US9567304, Compound G-25
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C25H27Cl2F3N4O7S2
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| Canonical SMILES |
CCS(=O)(=O)C1=C(C=C(C=C1)Cl)CN2C(=O)C3=CC(=C(C(=C3NC2=O)Cl)CN4CCCC4CNS(=O)(=O)C)OC(F)(F)F
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| InChI |
1S/C25H27Cl2F3N4O7S2/c1-3-43(39,40)20-7-6-15(26)9-14(20)12-34-23(35)17-10-19(41-25(28,29)30)18(21(27)22(17)32-24(34)36)13-33-8-4-5-16(33)11-31-42(2,37)38/h6-7,9-10,16,31H,3-5,8,11-13H2,1-2H3,(H,32,36)/t16-/m0/s1
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| InChIKey |
ADNJLXQZOZXZJU-INIZCTEOSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3444, 624118, 819062, 819405, 820462, 820497, 820533, 821796, 821952, 822752, 822753, 823075, 823149, 823150, 823869, 826036, 830674, 830999, 838629, 841773, 855181, 7885411, 7886738, 7887674, 8145524, 10317424, 10322321, 10322546, 11538719, 14901517, 16002058, 16014337, 24424483, 26705126, 26710788, 26712698, 26715076, 26717730, 26718716, 26736956, 29214752, 29225748, 46391986, 46393006, 46393137, 46393444, 46394156, 46530280, 49655320, 49975004
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Choline transporter (Malaria CT) | Target Info | Blocker | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. | |||
| REF 2 | Novel molecular targets for antimalarial chemotherapy. Int J Antimicrob Agents. 2007 Jul;30(1):4-10. | |||
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