Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z7MJ
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| Former ID |
DIB001097
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| Drug Name |
Prednisolone sodium metazoate
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| Synonyms |
Prednisolone metasulfobenzoate; Prednisolone sodium metasulfobenzoate; ATL-2502; ATL-2505; COLAL-PRED; Prednisolone sodium metazoate (COLAL); Program AZM-110; Prednisolone sodium metasulfobenzoate (COLAL), Alizyme; Prednisolone sodium metazoate (COLAL), Alizyme; Prednisolone (colonic delivery, COLAL, ulcerative colitis), Alizyme; Prednisolone (colonic delivery, COLAL, ulcerative colitis), Prometheus/TSD Japan
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory bowel disease [ICD-11: DD72; ICD-10: K50-K52] | Discontinued in Phase 2 | [1] | |
| Therapeutic Class |
Anticancer Agents
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| Company |
Alizyme
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| Structure |
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Download2D MOL |
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| Formula |
C28H31NaO9S
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| Canonical SMILES |
CC12CC(C3C(C1CCC2(C(=O)COC(=O)C4=CC(=CC=C4)S(=O)(=O)[O-])O)CCC5=CC(=O)C=CC35C)O.[Na+]
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| InChI |
1S/C28H32O9S.Na/c1-26-10-8-18(29)13-17(26)6-7-20-21-9-11-28(33,27(21,2)14-22(30)24(20)26)23(31)15-37-25(32)16-4-3-5-19(12-16)38(34,35)36;/h3-5,8,10,12-13,20-22,24,30,33H,6-7,9,11,14-15H2,1-2H3,(H,34,35,36);/q;+1/p-1/t20-,21-,22-,24+,26-,27-,28-;/m0./s1
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| InChIKey |
RWFZSORKWFPGNE-VDYYWZOJSA-M
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| CAS Number |
CAS 630-67-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid hormone receptor ERR (ESRR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008689) | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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