Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z6OT
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| Former ID |
DNC000969
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| Drug Name |
Mumbaistatin
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| Synonyms |
MUMBAISTATIN; CHEMBL238371
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C28H20O12
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| Canonical SMILES |
C1=CC2=C(C(=C1)O)C(=O)C3=C(C(=C(C=C3C2=O)O)C(=O)O)C(=O)C4=C(C=CC=C4O)C(=O)CCC(CC(=O)O)O
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| InChI |
1S/C28H20O12/c29-11(9-19(34)35)7-8-15(30)12-3-1-5-16(31)20(12)27(38)24-22-14(10-18(33)23(24)28(39)40)25(36)13-4-2-6-17(32)21(13)26(22)37/h1-6,10-11,29,31-33H,7-9H2,(H,34,35)(H,39,40)
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| InChIKey |
XFESZXMDORIFAO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucose-6-phosphate translocase (SLC37A4) | Target Info | Inhibitor | [1], [2] |
| KEGG Pathway | Carbohydrate digestion and absorption | |||
| Pathwhiz Pathway | Gluconeogenesis | |||
| Mitochondrial Electron Transport Chain | ||||
| Reactome | Glucose transport | |||
| WikiPathways | Metabolism of carbohydrates | |||
| Hexose transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Studies toward the total synthesis of mumbaistatin, a highly potent glucose-6-phosphate translocase inhibitor. Synthesis of a mumbaistatin analogue. J Org Chem. 2002 Dec 27;67(26):9248-56. | |||
| REF 2 | The chemical structure of mumbaistatin, a novel glucose-6-phosphate translocase inhibitor produced by Streptomyces sp. DSM 11641. J Antibiot (Tokyo). 2001 Apr;54(4):354-63. | |||
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