Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z5WG
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| Former ID |
DNC013652
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| Drug Name |
FAICAR
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| Synonyms |
Faicar; phosphoribosyl formamidocarboxamide; 5-Formamidoimidazole-4-carboxamide ribotide; 13018-54-7; CHEBI:18381; 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide; 5'-Phosphoribosyl-5-formamido-4-imidazolecarboxamide; 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide; 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide; 5-(Formylamino)-1-(5-O-Phosphono-Beta-D-Ribofuranosyl)-1h-Imidazole-4-Carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H15N4O9P
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| Canonical SMILES |
C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)NC=O)C(=O)N
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| InChI |
1S/C10H15N4O9P/c11-8(18)5-9(13-3-15)14(2-12-5)10-7(17)6(16)4(23-10)1-22-24(19,20)21/h2-4,6-7,10,16-17H,1H2,(H2,11,18)(H,13,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1
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| InChIKey |
ABCOOORLYAOBOZ-KQYNXXCUSA-N
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| CAS Number |
CAS 13018-54-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:18381
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphoribosylaminoimidazolecarboxamide formyltransferase (ATIC) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. J Biol Chem. 2007 Apr 27;282(17):13033-46. | |||
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