Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z0KE
|
|||
| Former ID |
DIB015577
|
|||
| Drug Name |
BX-044
|
|||
| Synonyms |
Plasminogen activator inhibitor inhibitors, Berlex; ZK-4044; PAI-1 inhibitors, Berlex
Click to Show/Hide
|
|||
| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Terminated | [1] | |
| Company |
Berlex Biosciences
|
|||
| Structure |
 |
Download2D MOL |
||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasminogen activator inhibitor (PAI) | Target Info | Inhibitor | [2] |
| KEGG Pathway | HIF-1 signaling pathway | |||
| p53 signaling pathway | ||||
| Hippo signaling pathway | ||||
| Complement and coagulation cascades | ||||
| Chagas disease (American trypanosomiasis) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of PAI-1: a new anti-thrombotic approach. Curr Drug Targets Cardiovasc Haematol Disord. 2002 Jun;2(1):27-42. | |||
| REF 2 | Characterization of a small molecule PAI-1 inhibitor, ZK4044. Thromb Res. 2005;115(4):341-50. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.