Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0YW9C
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| Former ID |
DNC008780
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| Drug Name |
1-benzyl-2,3-dimethyl-1H-indole-7-carboxylic acid
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| Synonyms |
CHEMBL515599; 1-benzyl-2,3-dimethyl-1H-indole-7-carboxylic acid; SCHEMBL6686678
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H17NO2
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| Canonical SMILES |
CC1=C(N(C2=C1C=CC=C2C(=O)O)CC3=CC=CC=C3)C
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| InChI |
1S/C18H17NO2/c1-12-13(2)19(11-14-7-4-3-5-8-14)17-15(12)9-6-10-16(17)18(20)21/h3-10H,11H2,1-2H3,(H,20,21)
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| InChIKey |
NSKDMNCONIAVGH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
| KEGG Pathway | PPAR signaling pathway | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | AP-1 transcription factor network | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| Transcriptional regulation of white adipocyte differentiation | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Transcriptional Regulation of White Adipocyte Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1745-8. | |||
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