Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YU1M
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| Former ID |
DIB011026
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| Drug Name |
G-207 virus construct
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| Synonyms |
HrR3; G-207; G-47; G-47delta; G-207 virus construct, Catherex; G-207 virus construct, MediGene; HSV mutants (glioma), NCI; Oncolytic herpes simplex virus (glioma), Catherex/MediGene
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| Indication | Glioma [ICD-11: 2A00.0; ICD-9: 191] | Phase 1/2 | [1] | |
| Company |
MediGene Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ribonucleotide reductase (RIR) | Target Info | Inhibitor | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00028158) Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer. U.S. National Institutes of Health. | |||
| REF 2 | Anti-tumor effect of oncolytic herpes simplex virus G47delta on human nasopharyngeal carcinoma. Chin J Cancer. 2011 Dec;30(12):831-41. | |||
| REF 3 | Utilizing tumor hypoxia to enhance oncolytic viral therapy in colorectal metastases. Ann Surg. 2004 Jun;239(6):892-9; discussion 899-902. | |||
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