Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YQ8V
|
|||
| Former ID |
DIB019602
|
|||
| Drug Name |
PMID24044867C8
|
|||
| Synonyms |
GTPL8195; BDBM50441572
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C24H21N3O3
|
|||
| Canonical SMILES |
COC1=CC(=CC(=C1OC)OC)C2=CC3=C(NC=C3C4=CC5=C(C=C4)NC=C5)N=C2
|
|||
| InChI |
1S/C24H21N3O3/c1-28-21-10-16(11-22(29-2)23(21)30-3)17-9-18-19(13-27-24(18)26-12-17)14-4-5-20-15(8-14)6-7-25-20/h4-13,25H,1-3H3,(H,26,27)
|
|||
| InChIKey |
UQHKXSZPEUNUDH-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mixed lineage kinase 3 (MAP3K11) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Non-alcoholic fatty liver disease (NAFLD) | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Pathway Interaction Database | Reelin signaling pathway | |||
| CDC42 signaling events | ||||
| IFN-gamma pathway | ||||
| RAC1 signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.