Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YK8M
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| Drug Name |
1,3,4-oxadiazole derivative 3
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| Synonyms |
PMID30107136-Compound-Example25
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| Drug Type |
Small molecule immunotherapy
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| Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
| Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
| Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
| Company |
AURIGENE DISCOVERY TECHNOLOGIES LIMITED
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| Structure |
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Download2D MOL |
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| Formula |
C16H27N7O7
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| Canonical SMILES |
C(CCN)CC(C1=NN=C(O1)C(CC(=O)N)NC(=O)NC(CCC(=O)O)C(=O)O)N
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| InChI |
1S/C16H27N7O7/c17-6-2-1-3-8(18)13-22-23-14(30-13)10(7-11(19)24)21-16(29)20-9(15(27)28)4-5-12(25)26/h8-10H,1-7,17-18H2,(H2,19,24)(H,25,26)(H,27,28)(H2,20,21,29)/t8-,9-,10-/m0/s1
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| InChIKey |
SIMOVBGEPUKIIM-GUBZILKMSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. | |||
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