Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y8PM
|
|||
| Former ID |
DCL000871
|
|||
| Drug Name |
LJP-1082
|
|||
| Synonyms |
Quinacrine azide; 3-Azido-9-((4-(diethylamino)-1-methylbutyl)amino)-7-methoxyacridine; AC1MI36Z; 73332-88-4; 1,4-Pentanediamine, N4-(6-azido-2-methoxy-9-acridinyl)-N1,N1-diethyl-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hughes syndrome [ICD-11: 4A45.Z; ICD-9: 289.81] | Discontinued in Phase 1 | [1] | |
| Company |
La Jolla Pharmaceutical
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C23H30N6O
|
|||
| Canonical SMILES |
CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)N=[N+]=[N-])OC
|
|||
| InChI |
1S/C23H30N6O/c1-5-29(6-2)13-7-8-16(3)25-23-19-11-9-17(27-28-24)14-22(19)26-21-12-10-18(30-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)
|
|||
| InChIKey |
OJZRYFDOXJOKNZ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 73332-88-4
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Beta-2-glycoprotein 1 (APOH) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014345) | |||
| REF 2 | Emergence of targeted immune therapies for systemic lupus. Expert Opin Emerg Drugs. 2005 Feb;10(1):53-65. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.