Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y6RZ
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Former ID |
DNC007661
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Drug Name |
1,2-bis(3-fluorophenyl)ethane-1,2-dione
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Synonyms |
1,2-bis(3-fluorophenyl)ethane-1,2-dione; CHEMBL242067; 3,3'-Difluorobenzil; SCHEMBL3169331; NIOZEPOIIGVTTO-UHFFFAOYSA-N; BDBM50209414
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H8F2O2
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Canonical SMILES |
C1=CC(=CC(=C1)F)C(=O)C(=O)C2=CC(=CC=C2)F
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InChI |
1S/C14H8F2O2/c15-11-5-1-3-9(7-11)13(17)14(18)10-4-2-6-12(16)8-10/h1-8H
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InChIKey |
NIOZEPOIIGVTTO-UHFFFAOYSA-N
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CAS Number |
CAS 70028-89-6
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
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REF 1 | Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils. Bioorg Med Chem. 2007 Jun 1;15(11):3801-17. |
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