Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y5DO
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Former ID |
DAP000118
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Drug Name |
Citalopram
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Synonyms |
Akarin; Celapram; Celexa; Celius; Ciazil; Cilift; Cipram; Ciprapine; Citabax; Citadur; Citalec; Citalopramum; Citopam; Cytalopram; Dalsan; Humorup; Nitalapram; Oropram; Pramcit; Recital; Seropram; Talam; Talohexal; Temperax; Vodelax; Zentius; Zetalo; Citalopram [Celexa]; [3H]Citalopram; Akarin (TN); Celapram (TN); Celexa (TN); Celius (TN); Ciazil (TN); Cilift (TN); Cipram (TN); Cipramil (TN); Ciprapine (TN); Citabax (TN); Citadur (TN); Citalec (TN); Citalopram [INN:BAN]; Citalopramum [INN-Latin]; Citaxin (TN); Citol (TN); Citopam (TN); Citox (TN); Citrol (TN); Dalsan (TN); Lu 10-171; Recital (TN); Seropram (TN); Talam (TN); Zentius (TN); Zetalo (TN); AE-641/00603021; Citalopram (USP/INN); Lu-10-171; 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile; 1,3-dihydro[3,4]benzofuran-5-carbonitrile; 1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
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Drug Type |
Small molecular drug
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Indication | Depression [ICD-11: 6A70-6A7Z; ICD-9: 311] | Approved | [1], [2] | |
Therapeutic Class |
Antidepressants
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Company |
Forest Laboratories, Inc
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Structure |
Download2D MOL |
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Formula |
C20H21FN2O
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Canonical SMILES |
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
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InChI |
1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
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InChIKey |
WSEQXVZVJXJVFP-UHFFFAOYSA-N
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CAS Number |
CAS 59729-33-8
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PubChem Compound ID | ||||
PubChem Substance ID |
9775, 855965, 4445124, 7978955, 8151789, 14826333, 24723457, 29221926, 46508746, 47656601, 47730750, 47879631, 48253450, 48415786, 48493834, 49699144, 49985355, 50104852, 51092001, 53788845, 56313600, 56413158, 57321451, 80123691, 80953770, 85209895, 85787315, 87690083, 90340852, 92307844, 92309285, 92711474, 99418031, 103177051, 104170209, 104301562, 121362384, 124570949, 124749575, 124879738, 124879739, 125353996, 126440716, 126525331, 126630818, 126657311, 126666544, 127275913, 127275914, 127275915
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ChEBI ID |
CHEBI:77397
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ADReCS Drug ID | BADD_D00475 ; BADD_D00476 | |||
SuperDrug ATC ID |
N06AB04
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SuperDrug CAS ID |
cas=059729338
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Target and Pathway | Top | |||
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Target(s) | Serotonin transporter (SERT) | Target Info | Modulator | [3] |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
WikiPathways | Monoamine Transport | |||
SIDS Susceptibility Pathways | ||||
NRF2 pathway | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7547). | |||
REF 2 | Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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