Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y4YV
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| Former ID |
DIB020931
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| Drug Name |
schisandrin A
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| Synonyms |
(-)-deoxyschisandrin; (-)-dimethylgomisin J
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C24H32O6
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| Canonical SMILES |
CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC
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| InChI |
1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+
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| InChIKey |
JEJFTTRHGBKKEI-OKILXGFUSA-N
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| CAS Number |
CAS 61281-38-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
622069, 10252559, 15031010, 17489907, 26725286, 46231260, 57348114, 60811184, 76207842, 88785233, 92710583, 95154777, 103559573, 104440860, 124798645, 126631730, 126658098, 135111772, 135652716, 137238557, 137331352, 143481378, 152099875, 162187702, 163123649, 179342389, 204360448, 228518455, 248186130, 252163660
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Pregnane X receptor (NR1I2) | Target Info | Agonist | [2] |
| WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
| Nuclear Receptors Meta-Pathway | ||||
| Pregnane X Receptor pathway | ||||
| Drug Induction of Bile Acid Pathway | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2769). | |||
| REF 2 | Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and inc... J Pharmacol Exp Ther. 2006 Mar;316(3):1369-77. | |||
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