Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y4EM
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| Former ID |
DIB008243
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| Drug Name |
Thrombomodulin
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| Synonyms |
THRODULIN Inj; MB-015; MR-33; Thrombomodulin, Mochida/JCR
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| Indication | Disseminated intravascular coagulation [ICD-11: 3B20; ICD-10: D65; ICD-9: 286.6] | Discontinued in Phase 3 | [1] | |
| Company |
Mochida Pharmaceutical Co Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thrombomodulin (THBD) | Target Info | Modulator | [2] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||
| Reactome | Common Pathway of Fibrin Clot Formation | |||
| Cell surface interactions at the vascular wall | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Nuclear Receptors Meta-Pathway | ||||
| Vitamin D Receptor Pathway | ||||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| Cell surface interactions at the vascular wall | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002139) | |||
| REF 2 | Thrombomodulin. Nihon Yakurigaku Zasshi. 2000 Nov;116(5):283-9. | |||
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